MHRA issues safety information on medicines for healthcare professionals

Friday 4th May 2007

The MHRA has compiled a list of letters sent to UK healthcare professionals in April 2007, to deliver new safety information and advice. Topics include:

• Mabthera® (rituximab): reports of progressive multifocal leukoencephalopathy in unapproved indications of systemic lupus erythematosus and vasculitis.

• Pioglitazone-containing products: risk of fractures in women on long-term treatment.

• Cabaser® (cabergoline): pathological gambling and increased libido are potential class effects of dopamine agonists.

• Desmopressin: removal of primary nocturnal enuresis indication.

• Ketek® (telithromycin): important information about restricted indications, contraindications and safety measures.

• Ventolin® (salbutamol): new prescribing advice for obstetric use in management of preterm labour and use in respiratory disease.

New Electronic Library for Medicines 2/5/2007